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Reduction of Urease Activity by Interaction with the Flap Covering the Active Site

With the increasing appreciation for the human microbiome coupled with the global rise of antibiotic resistant organisms, it is imperative that new methods be developed to specifically target pathogens. To that end, a novel computational approach was devised to identify compounds that reduce the act...

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Detalhes bibliográficos
Publicado no:J Chem Inf Model
Main Authors: Macomber, Lee, Minkara, Mona S., Hausinger, Robert P., Merz, Kenneth M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4491936/
https://ncbi.nlm.nih.gov/pubmed/25594724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ci500562t
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