Human dCTP pyrophosphatase 1 promotes breast cancer cell growth and stemness through the modulation on 5-methyl-dCTP metabolism and global hypomethylation

Human DCTPP1 (dCTP pyrophosphatase 1), also known as XTP3-transactivated protein A, belongs to MazG-like nucleoside triphosphate pyrophosphatase (NTP-PPase) superfamily. Being a newly identified pyrophosphatase, its relevance to tumorigenesis and the mechanisms are not well investigated. In the pres...

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Publicado en:Oncogenesis
Autores principales: Song, F-f, Xia, L-l, Ji, P, Tang, Y-b, Huang, Z-m, Zhu, L, Zhang, J, Wang, J-q, Zhao, G-p, Ge, H-l, Zhang, Y, Wang, Y
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2015
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4491611/
https://ncbi.nlm.nih.gov/pubmed/26075750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oncsis.2015.10
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