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Colonic mucosal gene expression and genotype in irritable bowel syndrome patients with normal or elevated fecal bile acid excretion

The mucosal gene expression in rectosigmoid mucosa (RSM) in irritable bowel syndrome with diarrhea (IBS-D) is unknown. Our objectives were, first, to study mRNA expression [by RT(2) PCR of 19 genes pertaining to tight junctions, immune activation, intestinal ion transport and bile acid (BA) homeosta...

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Pubblicato in:Am J Physiol Gastrointest Liver Physiol
Autori principali: Camilleri, Michael, Carlson, Paula, Acosta, Andres, Busciglio, Irene
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4491506/
https://ncbi.nlm.nih.gov/pubmed/25930081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00080.2015
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