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Eos is redundant for T regulatory cell function, but plays an important role in IL-2 and Th17 production by CD4(+) T conventional cells
Eos is a transcription factor that belongs to the Ikaros family of transcription factors. Eos has been reported to be a T regulatory cell (Treg) signature gene, to play a critical role in Treg suppressor functions, and to maintain Treg stability. We have utilized mice with a global deficiency of Eos...
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| Опубликовано в: : | J Immunol |
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| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4491037/ https://ncbi.nlm.nih.gov/pubmed/26062998 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500627 |
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