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Induction of HER2 Immunity in Outbred Domestic Cats by DNA Electrovaccination

Domestic cats share human living environments and genetic traits. They develop spontaneous feline mammary carcinoma (FMC) with histopathology similar to human breast cancer. HER2 and AKT phosphorylation was demonstrated in primary FMC by immunoblot, indicating HER2 as a therapeutic target. FMC lines...

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Detalhes bibliográficos
Publicado no:Cancer Immunol Res
Main Authors: Gibson, Heather, Veenstra, Jesse, Jones, Richard, Vaishampayan, Ulka, Sauerbrey, Michele, Bepler, Gerold, Lum, Lawrence, Reyes, Joyce, Weise, Amy, Wei, Wei-Zen
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4491035/
https://ncbi.nlm.nih.gov/pubmed/25711535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-14-0175
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