Functional heterogeneity and anti-mycobacterial effects of mouse mucosal associated invariant T (MAIT) cells specific for riboflavin metabolites()

Mucosal associated invariant T (MAIT) cells have a semi-invariant TCR Vα chain, and their optimal development is dependent upon commensal flora and expression of the non-polymorphic MHC class I-like molecule MR1. MAIT cells are activated in an MR1-restricted manner by diverse strains of bacteria and...

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Veröffentlicht in:J Immunol
Hauptverfasser: Sakala, Isaac G., Kjer-Nielsen, Lars, Eickhoff, Christopher S., Wang, Xiaoli, Blazevic, Azra, Liu, Ligong, Fairlie, David P., Rossjohn, Jamie, McCluskey, James, Fremont, Daved H., Hansen, Ted H., Hoft, Daniel F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4490942/
https://ncbi.nlm.nih.gov/pubmed/26063000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402545
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