Fluctuations between multiple EF-G-induced chimeric tRNA states during translocation on the ribosome

The coupled translocation of transfer RNA and messenger RNA through the ribosome entails large-scale structural rearrangements, including step-wise movements of the tRNAs. Recent structural work has visualized intermediates of translocation induced by elongation factor G (EF-G) with tRNAs trapped in...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Adio, Sarah, Senyushkina, Tamara, Peske, Frank, Fischer, Niels, Wintermeyer, Wolfgang, Rodnina, Marina V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Pub. Group 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4490557/
https://ncbi.nlm.nih.gov/pubmed/26072700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8442
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