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Targeted siRNA Screens Identify ER-to-Mitochondrial Calcium Exchange in Autophagy and Mitophagy Responses in RPE1 Cells

Autophagy is an important stress response pathway responsible for the removal and recycling of damaged or redundant cytosolic constituents. Mitochondrial damage triggers selective mitochondrial autophagy (mitophagy), mediated by a variety of response factors including the Pink1/Parkin system. Using...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: MacVicar, Thomas D. B., Mannack, Lilith V. J. C., Lees, Robert M., Lane, Jon D.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4490499/
https://ncbi.nlm.nih.gov/pubmed/26110381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms160613356
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