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Acetic Acid-Catalyzed Formation of N-Phenylphthalimide from Phthalanilic Acid: A Computational Study of the Mechanism

In glacial acetic acid, phthalanilic acid and its monosubstituents are known to be converted to the corresponding phthalimides in relatively good yields. In this study, we computationally investigated the experimentally proposed two-step (addition-elimination or cyclization-dehydration) mechanism at...

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Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Takahashi, Ohgi, Kirikoshi, Ryota, Manabe, Noriyoshi
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4490437/
https://ncbi.nlm.nih.gov/pubmed/26030675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms160612174
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