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Acetic Acid-Catalyzed Formation of N-Phenylphthalimide from Phthalanilic Acid: A Computational Study of the Mechanism

In glacial acetic acid, phthalanilic acid and its monosubstituents are known to be converted to the corresponding phthalimides in relatively good yields. In this study, we computationally investigated the experimentally proposed two-step (addition-elimination or cyclization-dehydration) mechanism at...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Takahashi, Ohgi, Kirikoshi, Ryota, Manabe, Noriyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4490437/
https://ncbi.nlm.nih.gov/pubmed/26030675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms160612174
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