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Acetic Acid-Catalyzed Formation of N-Phenylphthalimide from Phthalanilic Acid: A Computational Study of the Mechanism

In glacial acetic acid, phthalanilic acid and its monosubstituents are known to be converted to the corresponding phthalimides in relatively good yields. In this study, we computationally investigated the experimentally proposed two-step (addition-elimination or cyclization-dehydration) mechanism at...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Takahashi, Ohgi, Kirikoshi, Ryota, Manabe, Noriyoshi
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4490437/
https://ncbi.nlm.nih.gov/pubmed/26030675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms160612174
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