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Structural basis of asymmetric DNA methylation and ATP-triggered long-range diffusion by EcoP15I

Type III R–M enzymes were identified >40 years ago and yet there is no structural information on these multisubunit enzymes. Here we report the structure of a Type III R–M system, consisting of the entire EcoP15I complex (Mod(2)Res(1)) bound to DNA. The structure suggests how ATP hydrolysis is co...

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Vydáno v:Nat Commun
Hlavní autoři: Gupta, Yogesh K., Chan, Siu-Hong, Xu, Shuang-yong, Aggarwal, Aneel K.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Pub. Group 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4490356/
https://ncbi.nlm.nih.gov/pubmed/26067164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8363
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