Asymmetric DNA recognition by the OkrAI endonuclease, an isoschizomer of BamHI

Restriction enzymes share little or no sequence homology with the exception of isoschizomers, or enzymes that recognize and cleave the same DNA sequence. We present here the structure of a BamHI isoschizomer, OkrAI, bound to the same DNA sequence (TATGGATCCATA) as that cocrystallized with BamHI. We...

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Detalles Bibliográficos
Main Authors: Vanamee, Éva Scheuring, Viadiu, Hector, Chan, Siu-Hong, Ummat, Ajay, Hartline, Adrian M., Xu, Shuang-yong, Aggarwal, Aneel K.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2011
Assuntos:
Structural Biology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025578/
https://ncbi.nlm.nih.gov/pubmed/20833632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq779
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