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Tumor necrosis factor-α induces a biphasic change in claudin-2 expression in tubular epithelial cells: role in barrier functions

The inflammatory cytokine tumor necrosis factor-α (TNF-α) is a pathogenic factor in acute and chronic kidney disease. TNF-α is known to alter expression of epithelial tight junction (TJ) proteins; however, the underlying mechanisms and the impact of this effect on epithelial functions remain poorly...

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Détails bibliographiques
Publié dans:Am J Physiol Cell Physiol
Auteurs principaux: Amoozadeh, Yasaman, Dan, Qinghong, Xiao, Jenny, Waheed, Faiza, Szászi, Katalin
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4490324/
https://ncbi.nlm.nih.gov/pubmed/25948735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00388.2014
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