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A novel cinnamon-related natural product with Pim-1 inhibitory activity inhibits leukemia and skin cancer
The Pim-1 kinase regulates cell survival, proliferation and differentiation and is overexpressed frequently in many malignancies including leukemia and skin cancer. In this study, we used kinase profiling analysis to demonstrate that 2′-hydroxycinnamicadelhyde (2′-HCA), a compound found in cinnamon,...
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| Vydáno v: | Cancer Res |
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| Hlavní autoři: | , , , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4490130/ https://ncbi.nlm.nih.gov/pubmed/25948588 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-3655 |
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