Characterization of PD-L1 Expression and Associated T cell Infiltrates in Metastatic Melanoma Samples from Variable Anatomic Sites

PURPOSE: Programmed death ligand-1 (PD-L1) tumor expression represents a mechanism of immune escape for melanoma cells. Drugs blocking PD-L1 or its receptor have shown unprecedented activity in melanoma, and our purpose was to characterize tumor PD-L1 expression and associated T-cell infiltration in...

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Bibliografiske detaljer
Udgivet i:Clin Cancer Res
Main Authors: Kluger, Harriet M., Zito, Christopher R., Barr, Meaghan L., Baine, Marina K., Chiang, Veronica L.S., Sznol, Mario, Rimm, David L., Chen, Lieping, Jilaveanu, Lucia B.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4490112/
https://ncbi.nlm.nih.gov/pubmed/25788491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-3073
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