Targeting interleukin-11 receptor in leukemia and lymphoma: A functional ligand-directed study and hematopathology analysis of patient-derived specimens

PURPOSE: The interleukin-11 receptor (IL-11R) is an established molecular target in primary tumors of bone, such as osteosarcoma, and in secondary bone metastases from solid tumors such as prostate cancer. However, its potential role in management of hematopoietic malignancies has not yet been deter...

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Dettagli Bibliografici
Pubblicato in:Clin Cancer Res
Autori principali: Karjalainen, Katja, Jaalouk, Diana E., Bueso-Ramos, Carlos, Bover, Laura, Sun, Yan, Kuniyasu, Akihiko, Driessen, Wouter H. P., Cardó-Vila, Marina, Rietz, Cecilia, Zurita, Amado J., O’Brien, Susan, Kantarjian, Hagop M., Cortes, Jorge E., Calin, George A., Koivunen, Erkki, Arap, Wadih, Pasqualini, Renata
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4490100/
https://ncbi.nlm.nih.gov/pubmed/25779950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-3059
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