Targeting interleukin-11 receptor in leukemia and lymphoma: A functional ligand-directed study and hematopathology analysis of patient-derived specimens

PURPOSE: The interleukin-11 receptor (IL-11R) is an established molecular target in primary tumors of bone, such as osteosarcoma, and in secondary bone metastases from solid tumors such as prostate cancer. However, its potential role in management of hematopoietic malignancies has not yet been deter...

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發表在:Clin Cancer Res
Main Authors: Karjalainen, Katja, Jaalouk, Diana E., Bueso-Ramos, Carlos, Bover, Laura, Sun, Yan, Kuniyasu, Akihiko, Driessen, Wouter H. P., Cardó-Vila, Marina, Rietz, Cecilia, Zurita, Amado J., O’Brien, Susan, Kantarjian, Hagop M., Cortes, Jorge E., Calin, George A., Koivunen, Erkki, Arap, Wadih, Pasqualini, Renata
格式: Artigo
語言:Inglês
出版: 2015
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4490100/
https://ncbi.nlm.nih.gov/pubmed/25779950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-3059
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