Targeting interleukin-11 receptor in leukemia and lymphoma: A functional ligand-directed study and hematopathology analysis of patient-derived specimens

PURPOSE: The interleukin-11 receptor (IL-11R) is an established molecular target in primary tumors of bone, such as osteosarcoma, and in secondary bone metastases from solid tumors such as prostate cancer. However, its potential role in management of hematopoietic malignancies has not yet been deter...

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Publicado en:Clin Cancer Res
Autores principales: Karjalainen, Katja, Jaalouk, Diana E., Bueso-Ramos, Carlos, Bover, Laura, Sun, Yan, Kuniyasu, Akihiko, Driessen, Wouter H. P., Cardó-Vila, Marina, Rietz, Cecilia, Zurita, Amado J., O’Brien, Susan, Kantarjian, Hagop M., Cortes, Jorge E., Calin, George A., Koivunen, Erkki, Arap, Wadih, Pasqualini, Renata
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4490100/
https://ncbi.nlm.nih.gov/pubmed/25779950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-3059
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