Targeting interleukin-11 receptor in leukemia and lymphoma: A functional ligand-directed study and hematopathology analysis of patient-derived specimens

PURPOSE: The interleukin-11 receptor (IL-11R) is an established molecular target in primary tumors of bone, such as osteosarcoma, and in secondary bone metastases from solid tumors such as prostate cancer. However, its potential role in management of hematopoietic malignancies has not yet been deter...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Karjalainen, Katja, Jaalouk, Diana E., Bueso-Ramos, Carlos, Bover, Laura, Sun, Yan, Kuniyasu, Akihiko, Driessen, Wouter H. P., Cardó-Vila, Marina, Rietz, Cecilia, Zurita, Amado J., O’Brien, Susan, Kantarjian, Hagop M., Cortes, Jorge E., Calin, George A., Koivunen, Erkki, Arap, Wadih, Pasqualini, Renata
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4490100/
https://ncbi.nlm.nih.gov/pubmed/25779950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-3059
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