Structural and functional analysis of the GADD34:PP1 eIF2α phosphatase

The attenuation of protein synthesis via the phosphorylation of eIF2α is a major stress response of all eukaryotic cells. The Growth Arrest and DNA-damaged protein 34 (GADD34) bound to the serine/threonine protein phosphatase 1 (PP1) is the necessary eIF2α phosphatase complex that returns mammalian...

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Bibliographic Details
Published in:Cell Rep
Main Authors: Choy, Meng S., Yusoff, Permeen, Lee, Irene C., Newton, Jocelyn C., Goh, Catherine W., Page, Rebecca, Shenolikar, Shirish, Peti, Wolfgang
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4489983/
https://ncbi.nlm.nih.gov/pubmed/26095357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.05.043
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