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Rett Syndrome: Reaching for Clinical Trials
Rett syndrome (RTT) is a syndromic autism spectrum disorder caused by loss-of-function mutations in MECP2. The methyl CpG binding protein 2 binds methylcytosine and 5-hydroxymethycytosine at CpG sites in promoter regions of target genes, controlling their transcription by recruiting co-repressors an...
Uloženo v:
| Vydáno v: | Neurotherapeutics |
|---|---|
| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Springer US
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4489949/ https://ncbi.nlm.nih.gov/pubmed/25861995 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-015-0353-y |
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