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ON EXPERIMENTAL MODELS OF RETT SYNDROME BASED ON Mecp2 DYSFUNCTION

Rett syndrome (RTT) is a neurodevelopmental disorder predominantly occurring in females with an incidence of 1:10,000 births and caused by sporadic mutations in the MECP2 gene, which encodes methyl-CpG-binding protein-2, an epigenetic transcription factor that binds methylated DNA. The clinical hall...

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Detalhes bibliográficos
Main Authors: Calfa, Gaston, Percy, Alan K., Pozzo-Miller, Lucas
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3059199/
https://ncbi.nlm.nih.gov/pubmed/21239731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1258/ebm.2010.010261
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