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ON EXPERIMENTAL MODELS OF RETT SYNDROME BASED ON Mecp2 DYSFUNCTION
Rett syndrome (RTT) is a neurodevelopmental disorder predominantly occurring in females with an incidence of 1:10,000 births and caused by sporadic mutations in the MECP2 gene, which encodes methyl-CpG-binding protein-2, an epigenetic transcription factor that binds methylated DNA. The clinical hall...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3059199/ https://ncbi.nlm.nih.gov/pubmed/21239731 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1258/ebm.2010.010261 |
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