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Rett Syndrome: Reaching for Clinical Trials

Rett syndrome (RTT) is a syndromic autism spectrum disorder caused by loss-of-function mutations in MECP2. The methyl CpG binding protein 2 binds methylcytosine and 5-hydroxymethycytosine at CpG sites in promoter regions of target genes, controlling their transcription by recruiting co-repressors an...

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Detalhes bibliográficos
Publicado no:Neurotherapeutics
Main Authors: Pozzo-Miller, Lucas, Pati, Sandipan, Percy, Alan K.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4489949/
https://ncbi.nlm.nih.gov/pubmed/25861995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-015-0353-y
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