Huaier Extract Induces Autophagic Cell Death by Inhibiting the mTOR/S6K Pathway in Breast Cancer Cells

Huaier extract is attracting increased attention due to its biological activities, including antitumor, anti-parasite and immunomodulatory effects. Here, we investigated the role of autophagy in Huaier-induced cytotoxicity in MDA-MB-231, MDA-MB-468 and MCF7 breast cancer cells. Huaier treatment inhi...

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Udgivet i:PLoS One
Main Authors: Wang, Xiaolong, Qi, Wenwen, Li, Yaming, Zhang, Ning, Dong, Lun, Sun, Mingjuan, Cun, Jinjing, Zhang, Yan, Lv, Shangge, Yang, Qifeng
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4489895/
https://ncbi.nlm.nih.gov/pubmed/26134510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0131771
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