Reversibility of Defective Hematopoiesis Caused by Telomere Shortening in Telomerase Knockout Mice

Telomere shortening is common in bone marrow failure syndromes such as dyskeratosis congenita (DC), aplastic anemia (AA) and myelodysplastic syndromes (MDS). However, improved knowledge of the lineage-specific consequences of telomere erosion and restoration of telomere length in hematopoietic proge...

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Vydáno v:PLoS One
Hlavní autoři: Raval, Aparna, Behbehani, Gregory K., Nguyen, Le Xuan Truong, Thomas, Daniel, Kusler, Brenda, Garbuzov, Alina, Ramunas, John, Holbrook, Colin, Park, Christopher Y., Blau, Helen, Nolan, Garry P., Artandi, Steven E., Mitchell, Beverly S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4489842/
https://ncbi.nlm.nih.gov/pubmed/26133370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0131722
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