Reversibility of Defective Hematopoiesis Caused by Telomere Shortening in Telomerase Knockout Mice

Telomere shortening is common in bone marrow failure syndromes such as dyskeratosis congenita (DC), aplastic anemia (AA) and myelodysplastic syndromes (MDS). However, improved knowledge of the lineage-specific consequences of telomere erosion and restoration of telomere length in hematopoietic proge...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Raval, Aparna, Behbehani, Gregory K., Nguyen, Le Xuan Truong, Thomas, Daniel, Kusler, Brenda, Garbuzov, Alina, Ramunas, John, Holbrook, Colin, Park, Christopher Y., Blau, Helen, Nolan, Garry P., Artandi, Steven E., Mitchell, Beverly S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4489842/
https://ncbi.nlm.nih.gov/pubmed/26133370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0131722
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