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Reproducibility of Variant Calls in Replicate Next Generation Sequencing Experiments

Nucleotide alterations detected by next generation sequencing are not always true biological changes but could represent sequencing errors. Even highly accurate methods can yield substantial error rates when applied to millions of nucleotides. In this study, we examined the reproducibility of nucleo...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Qi, Yuan, Liu, Xiuping, Liu, Chang-gong, Wang, Bailing, Hess, Kenneth R., Symmans, W. Fraser, Shi, Weiwei, Pusztai, Lajos
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4489803/
https://ncbi.nlm.nih.gov/pubmed/26136146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0119230
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