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Reproducibility of Variant Calls in Replicate Next Generation Sequencing Experiments

Nucleotide alterations detected by next generation sequencing are not always true biological changes but could represent sequencing errors. Even highly accurate methods can yield substantial error rates when applied to millions of nucleotides. In this study, we examined the reproducibility of nucleo...

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書目詳細資料
發表在:PLoS One
Main Authors: Qi, Yuan, Liu, Xiuping, Liu, Chang-gong, Wang, Bailing, Hess, Kenneth R., Symmans, W. Fraser, Shi, Weiwei, Pusztai, Lajos
格式: Artigo
語言:Inglês
出版: Public Library of Science 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4489803/
https://ncbi.nlm.nih.gov/pubmed/26136146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0119230
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