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Reproducibility of Variant Calls in Replicate Next Generation Sequencing Experiments

Nucleotide alterations detected by next generation sequencing are not always true biological changes but could represent sequencing errors. Even highly accurate methods can yield substantial error rates when applied to millions of nucleotides. In this study, we examined the reproducibility of nucleo...

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Podrobná bibliografie
Vydáno v:PLoS One
Hlavní autoři: Qi, Yuan, Liu, Xiuping, Liu, Chang-gong, Wang, Bailing, Hess, Kenneth R., Symmans, W. Fraser, Shi, Weiwei, Pusztai, Lajos
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4489803/
https://ncbi.nlm.nih.gov/pubmed/26136146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0119230
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