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Lack of sufficiently strong informative features limits the potential of gene expression analysis as predictive tool for many clinical classification problems
BACKGROUND: Our goal was to examine how various aspects of a gene signature influence the success of developing multi-gene prediction models. We inserted gene signatures into three real data sets by altering the expression level of existing probe sets. We varied the number of probe sets perturbed (s...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3245512/ https://ncbi.nlm.nih.gov/pubmed/22132775 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-12-463 |
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