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Characterization of permeability, stability and anti-HIV-1 activity of decitabine and gemcitabine divalerate prodrugs
BACKGROUND: Over 25 drugs have been approved for the treatment of HIV-1 replication. All but one of these drugs is delivered as an oral medication. Previous studies have demonstrated that two drugs, decitabine and gemcitabine, have potent anti-HIV-1 activities and can work together in synergy to red...
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| Veröffentlicht in: | Antivir Chem Chemother |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4489529/ https://ncbi.nlm.nih.gov/pubmed/23994876 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3851/IMP2682 |
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