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Dual anti-HIV mechanism of clofarabine
BACKGROUND: HIV-1 replication kinetics inherently depends on the availability of cellular dNTPs for viral DNA synthesis. In activated CD4(+) T cells and other rapidly dividing cells, the concentrations of dNTPs are high and HIV-1 reverse transcription occurs in an efficient manner. In contrast, nond...
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| Publicado no: | Retrovirology |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4806454/ https://ncbi.nlm.nih.gov/pubmed/27009333 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-016-0254-0 |
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