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The roles of carboxylesterase and CYP isozymes on the in vitro metabolism of T-2 toxin

BACKGROUND: T-2 toxin poses a great threat to human health because it has the highest toxicity of the currently known trichothecene mycotoxins. To understand the in vivo toxicity and transformation mechanism of T-2 toxin, we investigated the role of one kind of principal phase I drug-metabolizing en...

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Publicat a:Mil Med Res
Autors principals: Lin, Ni-Ni, Chen, Jia, Xu, Bin, Wei, Xia, Guo, Lei, Xie, Jian-Wei
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4489217/
https://ncbi.nlm.nih.gov/pubmed/26140218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40779-015-0041-6
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