טוען...
Functional Constraint Profiling of a Viral Protein Reveals Discordance of Evolutionary Conservation and Functionality
Viruses often encode proteins with multiple functions due to their compact genomes. Existing approaches to identify functional residues largely rely on sequence conservation analysis. Inferring functional residues from sequence conservation can produce false positives, in which the conserved residue...
שמור ב:
| הוצא לאור ב: | PLoS Genet |
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| Main Authors: | , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Public Library of Science
2015
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4489113/ https://ncbi.nlm.nih.gov/pubmed/26132554 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005310 |
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