HIV-1 Quasispecies Delineation by Tag Linkage Deep Sequencing

Trade-offs between throughput, read length, and error rates in high-throughput sequencing limit certain applications such as monitoring viral quasispecies. Here, we describe a molecular-based tag linkage method that allows assemblage of short sequence reads into long DNA fragments. It enables haplot...

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Detalhes bibliográficos
Main Authors: Wu, Nicholas C., De La Cruz, Justin, Al-Mawsawi, Laith Q., Olson, C. Anders, Qi, Hangfei, Luan, Harding H., Nguyen, Nguyen, Du, Yushen, Le, Shuai, Wu, Ting-Ting, Li, Xinmin, Lewis, Martha J., Yang, Otto O., Sun, Ren
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4026136/
https://ncbi.nlm.nih.gov/pubmed/24842159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097505
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