TopBP1 Governs Hematopoietic Stem/Progenitor Cells Survival in Zebrafish Definitive Hematopoiesis

In vertebrate definitive hematopoiesis, nascent hematopoietic stem/progenitor cells (HSPCs) migrate to and reside in proliferative hematopoietic microenvironment for transitory expansion. In this process, well-established DNA damage response pathways are vital to resolve the replication stress, whic...

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Bibliographic Details
Published in:PLoS Genet
Main Authors: Gao, Lei, Li, Dantong, Ma, Ke, Zhang, Wenjuan, Xu, Tao, Fu, Cong, Jing, Changbin, Jia, Xiaoe, Wu, Shuang, Sun, Xin, Dong, Mei, Deng, Min, Chen, Yi, Zhu, Wenge, Peng, Jinrong, Wan, Fengyi, Zhou, Yi, Zon, Leonard I., Pan, Weijun
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4488437/
https://ncbi.nlm.nih.gov/pubmed/26131719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005346
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