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Expression of TopBP1 in hereditary breast cancer
TopBP1 protein displays structural as well as functional similarities to BRCA1 and is involved in DNA replication, DNA damage checkpoint response and transcriptional regulation. Aberrant expression of TopBP1 may lead to genomic instability and can have pathological consequences. In this study we aim...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Netherlands
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3358587/ https://ncbi.nlm.nih.gov/pubmed/22544570 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11033-012-1622-z |
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