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Rational Design and Adaptive Management of Combination Therapies for Hepatitis C Virus Infection

Recent discoveries of direct acting antivirals against Hepatitis C virus (HCV) have raised hopes of effective treatment via combination therapies. Yet rapid evolution and high diversity of HCV populations, combined with the reality of suboptimal treatment adherence, make drug resistance a clinical a...

詳細記述

保存先:
書誌詳細
出版年:PLoS Comput Biol
主要な著者: Ke, Ruian, Loverdo, Claude, Qi, Hangfei, Sun, Ren, Lloyd-Smith, James O.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4488346/
https://ncbi.nlm.nih.gov/pubmed/26125950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004040
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