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Rational Design and Adaptive Management of Combination Therapies for Hepatitis C Virus Infection

Recent discoveries of direct acting antivirals against Hepatitis C virus (HCV) have raised hopes of effective treatment via combination therapies. Yet rapid evolution and high diversity of HCV populations, combined with the reality of suboptimal treatment adherence, make drug resistance a clinical a...

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Detalles Bibliográficos
Publicado en:PLoS Comput Biol
Main Authors: Ke, Ruian, Loverdo, Claude, Qi, Hangfei, Sun, Ren, Lloyd-Smith, James O.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4488346/
https://ncbi.nlm.nih.gov/pubmed/26125950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004040
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