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Rational Design and Adaptive Management of Combination Therapies for Hepatitis C Virus Infection

Recent discoveries of direct acting antivirals against Hepatitis C virus (HCV) have raised hopes of effective treatment via combination therapies. Yet rapid evolution and high diversity of HCV populations, combined with the reality of suboptimal treatment adherence, make drug resistance a clinical a...

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Bibliografski detalji
Izdano u:PLoS Comput Biol
Glavni autori: Ke, Ruian, Loverdo, Claude, Qi, Hangfei, Sun, Ren, Lloyd-Smith, James O.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4488346/
https://ncbi.nlm.nih.gov/pubmed/26125950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004040
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