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Evolutionary Analysis of Human Immunodeficiency Virus Type 1 Therapies Based on Conditionally Replicating Vectors

Efforts to reduce the viral load of human immunodeficiency virus type 1 (HIV-1) during long-term treatment are challenged by the evolution of anti-viral resistance mutants. Recent studies have shown that gene therapy approaches based on conditionally replicating vectors (CRVs) could have many advant...

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Detalhes bibliográficos
Main Authors: Ke, Ruian, Lloyd-Smith, James O.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486895/
https://ncbi.nlm.nih.gov/pubmed/23133349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002744
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