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A tetravalent alphavirus-vector based Dengue vaccine provides effective immunity in an early life mouse model
Dengue viruses (DENV1-4) cause 390 million clinical infections every year, several hundred thousand of which progress to severe hemorrhagic and shock syndromes. Preexisting immunity resulting from a previous DENV infection is the major risk factor for severe dengue during secondary heterologous infe...
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| Veröffentlicht in: | Vaccine |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4487803/ https://ncbi.nlm.nih.gov/pubmed/24882043 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2014.05.053 |
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