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A tetravalent alphavirus-vector based Dengue vaccine provides effective immunity in an early life mouse model

Dengue viruses (DENV1-4) cause 390 million clinical infections every year, several hundred thousand of which progress to severe hemorrhagic and shock syndromes. Preexisting immunity resulting from a previous DENV infection is the major risk factor for severe dengue during secondary heterologous infe...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Vaccine
Hauptverfasser: Khalil, Syed Muaz, Tonkin, Daniel R., Mattocks, Melissa D., Snead, Andrew T., Johnston, Robert E., White, Laura J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4487803/
https://ncbi.nlm.nih.gov/pubmed/24882043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2014.05.053
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