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An Alphavirus-Based Adjuvant Enhances Serum and Mucosal Antibodies, T Cells, and Protective Immunity to Influenza Virus in Neonatal Mice
Neonatal immune responses to infection and vaccination are biased toward T(H)2 at the cost of proinflammatory T(H)1 responses needed to combat intracellular pathogens. However, upon appropriate stimulation, the neonatal immune system can induce adult-like T(H)1 responses. Here we report that a new c...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4136293/ https://ncbi.nlm.nih.gov/pubmed/24899195 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00327-14 |
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