An Alphavirus-Based Adjuvant Enhances Serum and Mucosal Antibodies, T Cells, and Protective Immunity to Influenza Virus in Neonatal Mice

Neonatal immune responses to infection and vaccination are biased toward T(H)2 at the cost of proinflammatory T(H)1 responses needed to combat intracellular pathogens. However, upon appropriate stimulation, the neonatal immune system can induce adult-like T(H)1 responses. Here we report that a new c...

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Hlavní autoři: Khalil, Syed Muaz, Tonkin, Daniel R., Snead, Andrew T., Parks, Griffith D., Johnston, Robert E., White, Laura J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2014
Témata:
Vaccines and Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136293/
https://ncbi.nlm.nih.gov/pubmed/24899195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00327-14
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