Inhibition and breaking of advanced glycation end-products (AGEs) with bis-2-aminoimidazole derivatives

Advanced glycation end-products (AGEs), unregulated modifications to host macromolecules that occur as a result of metabolic dysregulation, play a role in many diabetes related complications, inflammation and aging, and may lead to increased cardiovascular risk. Small molecules that have the ability...

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Bibliografske podrobnosti
izdano v:Tetrahedron Lett
Main Authors: Richardson, Mike A., Furlani, Robert E., Podell, Brendan K., Ackart, David F., Haugen, Jessica D., Melander, Roberta J., Melander, Christian, Basaraba, Randall J.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4487526/
https://ncbi.nlm.nih.gov/pubmed/26146419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2015.01.122
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