Limited efficacy of BMS-911543 in a murine model of Janus kinase 2 V617F myeloproliferative neoplasm

Activation of JAK2, frequently as a result of the JAK2(V617F) mutation, is a characteristic feature of the classical myeloproliferative neoplasms (MPN) polycythemia vera, essential thrombocythemia and myelofibrosis and is thought to be responsible for the constitutional symptoms associated with thes...

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Bibliografske podrobnosti
izdano v:Exp Hematol
Main Authors: Pomicter, Anthony D., Eiring, Anna M., Senina, Anna V., Zabriskie, Matthew S., Marvin, James E., Prchal, Josef T., O’Hare, Thomas, Deininger, Michael W.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4487517/
https://ncbi.nlm.nih.gov/pubmed/25912019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2015.03.006
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