Application Of Small Molecules Favoring Naïve Pluripotency during Human Embryonic Stem Cell Derivation

In mice, inhibition of both the fibroblast growth factor (FGF) mitogen-activated protein kinase kinase/extracellular-signal regulated kinase (MEK/Erk) and the Wnt signaling inhibitor glycogen synthase-3β (GSK3β) enables the derivation of mouse embryonic stem cells (mESCs) from nonpermissive strains...

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Bibliographic Details
Published in:Cell Reprogram
Main Authors: Van der Jeught, Margot, Taelman, Jasin, Duggal, Galbha, Ghimire, Sabitri, Lierman, Sylvie, Chuva de Sousa Lopes, Susana M., Deforce, Dieter, Deroo, Tom, De Sutter, Petra, Heindryckx, Björn
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc. 2015
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4487243/
https://ncbi.nlm.nih.gov/pubmed/26053517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cell.2014.0085
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