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Application Of Small Molecules Favoring Naïve Pluripotency during Human Embryonic Stem Cell Derivation
In mice, inhibition of both the fibroblast growth factor (FGF) mitogen-activated protein kinase kinase/extracellular-signal regulated kinase (MEK/Erk) and the Wnt signaling inhibitor glycogen synthase-3β (GSK3β) enables the derivation of mouse embryonic stem cells (mESCs) from nonpermissive strains...
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| 發表在: | Cell Reprogram |
|---|---|
| Main Authors: | , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Mary Ann Liebert, Inc.
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4487243/ https://ncbi.nlm.nih.gov/pubmed/26053517 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cell.2014.0085 |
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