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Radiosensitization of human glioma cells by tamoxifen is associated with the inhibition of PKC-ι activity in vitro

The present study aimed to investigate the radiosensitizing effects of tamoxifen (TAM), a non-steroidal anti-estrogen drug, in human glioma A172 and U251 cells in vitro. A colony-forming assay revealed that TAM enhances radiosensitivity in A172 and U251 cells. Treatment with TAM also increased the p...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: YANG, LEI, YUAN, XIAOPENG, WANG, JIE, GU, CHENG, ZHANG, HAOWEN, YU, JIAHUA, LIU, FENJU
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4487191/
https://ncbi.nlm.nih.gov/pubmed/26171054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2015.3195
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