Dgcr8 and Dicer are essential for sex chromosome integrity during meiosis in males

Small RNAs play crucial roles in regulating gene expression during mammalian meiosis. To investigate the function of microRNAs (miRNAs) and small interfering RNAs (siRNAs) during meiosis in males, we generated germ-cell-specific conditional deletions of Dgcr8 and Dicer in mice. Analysis of spermatoc...

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Detalles Bibliográficos
Publicado en:J Cell Sci
Main Authors: Modzelewski, Andrew J., Hilz, Stephanie, Crate, Elizabeth A., Schweidenback, Caterina T. H., Fogarty, Elizabeth A., Grenier, Jennifer K., Freire, Raimundo, Cohen, Paula E., Grimson, Andrew
Formato: Artigo
Idioma:Inglês
Publicado: The Company of Biologists 2015
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4487015/
https://ncbi.nlm.nih.gov/pubmed/25934699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.167148
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