Dgcr8 and Dicer are essential for sex chromosome integrity during meiosis in males

Small RNAs play crucial roles in regulating gene expression during mammalian meiosis. To investigate the function of microRNAs (miRNAs) and small interfering RNAs (siRNAs) during meiosis in males, we generated germ-cell-specific conditional deletions of Dgcr8 and Dicer in mice. Analysis of spermatoc...

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Veröffentlicht in:J Cell Sci
Hauptverfasser: Modzelewski, Andrew J., Hilz, Stephanie, Crate, Elizabeth A., Schweidenback, Caterina T. H., Fogarty, Elizabeth A., Grenier, Jennifer K., Freire, Raimundo, Cohen, Paula E., Grimson, Andrew
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists 2015
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4487015/
https://ncbi.nlm.nih.gov/pubmed/25934699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.167148
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