Dgcr8 and Dicer are essential for sex chromosome integrity during meiosis in males

Small RNAs play crucial roles in regulating gene expression during mammalian meiosis. To investigate the function of microRNAs (miRNAs) and small interfering RNAs (siRNAs) during meiosis in males, we generated germ-cell-specific conditional deletions of Dgcr8 and Dicer in mice. Analysis of spermatoc...

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Dettagli Bibliografici
Pubblicato in:J Cell Sci
Autori principali: Modzelewski, Andrew J., Hilz, Stephanie, Crate, Elizabeth A., Schweidenback, Caterina T. H., Fogarty, Elizabeth A., Grenier, Jennifer K., Freire, Raimundo, Cohen, Paula E., Grimson, Andrew
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Company of Biologists 2015
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4487015/
https://ncbi.nlm.nih.gov/pubmed/25934699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.167148
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