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Beta-cell regeneration from vimentin(+)/MafB(+) cells after STZ-induced extreme beta-cell ablation
Loss of functional beta-cells is fundamental in both type 1 and type 2 diabetes. In situ beta-cell regeneration therefore has garnered great interest as an approach to diabetes therapy. Here, after elimination of pre-existing beta cells by a single high-dose of streptozotocin (STZ), we demonstrated...
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| Izdano u: | Sci Rep |
|---|---|
| Glavni autori: | , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2015
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4486952/ https://ncbi.nlm.nih.gov/pubmed/26129776 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep11703 |
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