Beta-cell regeneration from vimentin(+)/MafB(+) cells after STZ-induced extreme beta-cell ablation

Loss of functional beta-cells is fundamental in both type 1 and type 2 diabetes. In situ beta-cell regeneration therefore has garnered great interest as an approach to diabetes therapy. Here, after elimination of pre-existing beta cells by a single high-dose of streptozotocin (STZ), we demonstrated...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Cheng, Yu, Kang, Hongjun, Shen, Jing, Hao, Haojie, Liu, Jiejie, Guo, Yelei, Mu, Yiming, Han, Weidong
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2015
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4486952/
https://ncbi.nlm.nih.gov/pubmed/26129776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep11703
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