Beta-cell regeneration from vimentin(+)/MafB(+) cells after STZ-induced extreme beta-cell ablation

Loss of functional beta-cells is fundamental in both type 1 and type 2 diabetes. In situ beta-cell regeneration therefore has garnered great interest as an approach to diabetes therapy. Here, after elimination of pre-existing beta cells by a single high-dose of streptozotocin (STZ), we demonstrated...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Cheng, Yu, Kang, Hongjun, Shen, Jing, Hao, Haojie, Liu, Jiejie, Guo, Yelei, Mu, Yiming, Han, Weidong
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4486952/
https://ncbi.nlm.nih.gov/pubmed/26129776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep11703
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