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Preferential reduction of β cells derived from Pax6- MafB- pathway in MafB deficient mice

During pancreatic development insulin(+) cells co-express the transcription factors MafB and Pax6, and transition from a MafA(−) to MafA(+) state. To examine the role of Pax6 and MafB in the development of β cells, we analyzed embryonic pancreata from Pax6- and MafB- deficient mice. Pax6 deficiency,...

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Detalhes bibliográficos
Main Authors: Nishimura, Wataru, Rowan, Sheldon, Salameh, Therese, Maas, Richard L., Bonner-Weir, Susan, Sell, Susan M., Sharma, Arun
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2435621/
https://ncbi.nlm.nih.gov/pubmed/18199433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2007.12.00
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