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Preferential reduction of β cells derived from Pax6- MafB- pathway in MafB deficient mice
During pancreatic development insulin(+) cells co-express the transcription factors MafB and Pax6, and transition from a MafA(−) to MafA(+) state. To examine the role of Pax6 and MafB in the development of β cells, we analyzed embryonic pancreata from Pax6- and MafB- deficient mice. Pax6 deficiency,...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2435621/ https://ncbi.nlm.nih.gov/pubmed/18199433 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2007.12.00 |
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